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Neurology
Multiple Sclerosis Edition
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Chapter 1
Multiple Sclerosis Basics

Last Updated: April 25, 2013
Chapter 2
MRI and New Imaging Technologies in Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 3
Currently Available Treatments for Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 4
Small-Molecule Treatments In Development for Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 5
Monoclonal Antibodies in Development for Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 6
Managing Symptoms in Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 7
Prognostic Factors in Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 8
Improving Immunosuppression and Immunomodulation Treatment Strategies in Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 9
Neuroprotection and Neuroregeneration in MS

Last Updated: April 25, 2013
Chapter 10
Complementary and Alternative Medicine in Multiple Sclerosis

Last Updated: April 25, 2013
Chapter 11
Adherence and Compliance in Multiple Sclerosis: Understanding Challenges and Implementing Solutions

Last Updated: April 25, 2013
Chapter 12
Cognitive Impairment in Multiple Sclerosis: Early Detection and Management

Last Updated: April 25, 2013
Chapter 13
Genetics of Multiple Sclerosis: Implications for MS Susceptibility, Prognosis, and Treatment Response

Last Updated: April 25, 2013

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Chapter 12 – Cognitive Impairment in Multiple Sclerosis: Early Detection and Management

Editor-In-Chief
Bruce A. Cohen Bruce A. Cohen, MD
Professor
Davee Department of Neurology
    and Clinical Neurosciences
Feinberg School of Medicine
Northwestern University
Chicago, Illinois

Contributing Editor
Ralph H. B. Benedict Ralph H. B. Benedict, PhD
Professor of Neurology, Psychiatry
    and Psychology
University at Buffalo
Buffalo General Hospital
Department of Neurology
Buffalo, New York
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Activity Goal
The goal of this CME/CE activity is to examine the pathophysiology, etiologic factors, classification, diagnostic criteria, and current and emerging strategies for treating and managing patients with multiple sclerosis.


Target Audience
This CME/CE activity is designed for neurologists, internal medicine specialists, family practice/primary care physicians, nurse specialists/nurse practitioners, physician assistants, and pharmacists who interact with and are involved in the management and treatment of patients with multiple sclerosis.

Learning Objectives
•   Integrate strategies during routine examinations to identify cognitive impairment in multiple sclerosis (MS) patients as early in the disease course as possible, recognizing the importance of this on patient outcomes.
•   Evaluate strategies/tools to identify and quantify cognitive impairment and its impact on disability in MS.
•   Analyze the potential impact of current and emerging treatments in the management of cognitive impairment in MS.

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CME Information: Physicians
Statement of Accreditation
Projects In Knowledge® is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation

Projects In Knowledge® designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.



CE Information: Nurses
Projects In Knowledge® (PIK) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Projects In Knowledge is also an approved provider by the California Board of Registered Nursing, Provider Number CEP-15227.

Upon completion of this course, participants will be awarded 1.17 nursing contact hour(s).

DISCLAIMER: Accreditation refers to educational content only and does not imply ANCC, CBRN, or PIK endorsement of any commercial product or service.



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Disclosure Information
The Disclosure Policy of Projects In Knowledge requires that presenters comply with the Standards for Commercial Support. All faculty are required to disclose any personal interest or relationship they or their spouse/partner have with the supporters of this activity or any commercial interest that is discussed in their presentation. Any discussions of unlabeled/unapproved uses of drugs or devices will also be disclosed in the course materials. For complete prescribing information on the products discussed during this CME/CE activity, please see your current Physicians' Desk Reference (PDR).

Bruce A. Cohen, MD, has received grant/research support through Northwestern University from Biogen Idec, EMD Serono, NIH, and Novartis; has received honoraria and participated in speakers bureaus of Bayer Pharmaceuticals, EMD Serono, Pfizer Inc, and Teva Neuroscience; has received consulting fees from Acorda Therapeutics, Biogen Idec, CVS-Caremark, EMD Serono, Genzyme, Novartis, Pfizer Inc, and Teva Neuroscience; and has ownership interest in Abbott Laboratories and CVS-Caremark.

Ralph H. B. Benedict, PhD, has received grant/research support from Acorda Therapeutics, Biogen Idec, and Shire; is on the advisory boards of and has received consulting fees from Actelion Pharmaceuticals US, Inc, Bayer HealthCare, Biogen Idec, and EMD Serono; has received honoraria from Bayer HealthCare and Teva Pharmaceuticals; and has received royalties from Psychological Assessment Resources.

Lauren A. Cerruto Medical Writer, has disclosed no significant relationships.

This chapter includes discussion of off-label and investigational uses of multiple sclerosis (MS) disease-modifying therapies and other treatments for the management of cognitive impairment in MS.

Peer Reviewer has disclosed no significant relationships.

Dorothy Caputo, MA, BSN, RN (lead nurse planner) has no significant relationships to disclose.
Bernadette Marie Makar, MSN, NP-C, APRN-C (nurse planner) has no significant relationships to disclose.

Projects In Knowledge’s staff members have no significant relationships to disclose.

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Conflicts of interest are thoroughly vetted by the Executive Committee of Projects In Knowledge. All conflicts are resolved prior to the beginning of the activity by the Trust In Knowledge peer review process.

The opinions expressed in this activity are those of the faculty and do not necessarily reflect those of Projects In Knowledge.

This CME/CE activity is provided by Projects In Knowledge solely as an educational service. Specific patient care decisions are the responsibility of the clinician caring for the patient.

Contract for Mutual Responsibility in CME/CE
Projects In Knowledge has developed the contract to demonstrate our commitment to providing the highest quality professional education to clinicians, and to help clinicians set educational goals to challenge and enhance their learning experience.

For more information on the contract, click here

Projects In Knowledge is a registered trademark of Projects In Knowledge, Inc.

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Launch Activity

 
Projects In Knowledge®


Peer Reviewed
These independent CME/CE activities are supported by an educational grant from Teva Neuroscience.

Teva




Release Date: April 26, 2012.

Termination Date: December 31, 2013.

Estimated time for completion of this activity:
CME: 2.00 hours
CNE: 1.17 hours

CME/CE Instructions
To obtain CME/CE credit for this activity:
  1. Read the chapter carefully.
  2. Complete/submit the posttest and evaluation.
  3. Instantly access and print out your certificate.

There is no fee for this activity.

For questions about content or obtaining CME credit, please contact us.































 
 




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